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Agenus Achieves Incyte Milestone

Initiation of a Phase I trial of INCAGN2385 triggers $5M payment

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By: Kristin Brooks

Managing Editor, Contract Pharma

Agenus Inc., an immune-oncology company developing immune checkpoint antibodies, cancer vaccines and adoptive cell therapies, achieved a cash milestone from Incyte for the initiation of a Phase I trial of INCAGN2385, an anti-LAG-3 antibody discovered by Agenus. Agenus received a $5 million payment and is eligible to receive as much as an additional $505 million in potential development, regulatory and commercial milestones from Incyte.    “This is the fourth antibody from our partnered p...

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